HEREDITARY BREAST CANCER

Maren T. Scheuner, M.D., M.P.H

Medical Director, GenRISK Prevention Program

Cedars-Sinai Medical Center

8700 Beverly Blvd., SSB-378

Los Angeles, CA 90048

e-mail: mscheuner@mailgate.csmc.edu

TABLE OF CONTENTS

Introduction

Genetic Epidemiology

Genes and Breast Cancer

Characteristics of Hereditary Breast Cancer

BRCA 1 and BRCA 2

Clinical Impact of Genetic Susceptibility Information

Application of Genetic Susceptibility Information

References